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Follow-up studies on cells taken from these patients showed that the DCA helped normalize cancer mitochondria to they could kill off cancer cells, along with other anti-tumour effects.
What's more, none of the patients reported significant side effects when taking DCA at the level prescribed. Michelakis say he's delighted with the results, which are published in the journal, Science Translational Medicine.
Joseph Megyesi, a neurosurgeon who is the chair of the board of directors for the Brain Tumour Foundation of Canada, expressed cautious optimism about the study, noting that false hopes have been raised before.
But Megyesi also said that patients "should be cautiously optimistic that this potential treatment may be effective down the road. Still, he said, if DCA is shown in further studies to be effective, the fact that it is already being used to treat mitochondrial diseases would make it easier for it to be approved for a new use.
Michelakis notes that all of the studies they've undertaken thus far on DCA have come with the support of the University of Alberta and public donations. That's in part because DCA is a commonly available compound that is not patented or owned by any drug firm. Pharmaceutical companies have not been interested in funding further research on DCA since the treatment won't make them a profit.
He also notes that similar studies will soon start on the use of DCA for treating breast cancer, and could be extended to other cancers, too. The University of Alberta's Dr. Evangelos Michelakis and a colleague look at a brain scan in Edmonton, Wednesday, May 12, Cancer Society worried by self-medication reports. Small molecule offers hope for cancer treatment. At his plea hearing in May , Gaber admitted selling what he falsely claimed was the experimental cancer drug sodium dichloroacetate, also known as DCA, to at least 65 victims in the United States, Canada, the United Kingdom, Belgium and the Netherlands between October and November Gaber also admitted to selling more than pirated copies of business software between February and December As part of the plea agreement, Gaber agreed to forfeit or cancel any website, domain name or Internet services account related to this fraud scheme.
Breuer of the Criminal Division. Burke, U. Attorney for the District of Arizona. In actuality, Gaber admitted he sent victims a white powdery substance that was later determined through laboratory tests to contain starch, dextrin, dextrose or lactose, and contained no DCA.
According to court documents, along with the counterfeit DCA, the packages also contained a fraudulent certificate of analysis from a fictitious laboratory and instructions on how to dilute and ingest the bogus DCA.
DCA is an experimental cancer drug that has not yet been approved by the U.
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