A FET cycle will take approximately 6 to 8 weeks. A cycle typically begins with an injection Prostap on approximately day 21 of your cycle to suppress the normal ovarian cycle. After the course of Prostap you will have a bleed and you will need a baseline assessment involving bloodwork and ultrasound.
Depending on the test results, your doctor may instruct you to begin daily tablets of estrogen to build the uterine lining. After a designated period of time on the estrogen tablets, you will return for a transvaginal ultrasound lining check.
If the lining check demonstrates that your hormone levels are appropriate and your endometrial lining has thickened, your doctor will likely instruct you to add vaginal pessaries of progesterone to your medication regimen.
Your nurse will then confirm an FET date and you will come in for your transfer several days later. Estrogen and progesterone continue after the transfer, and through to the blood pregnancy test about 2 weeks later. The embryo transfer is a simple procedure that only takes about 5 minutes to complete. There is no anaesthesia or recovery time needed. When your nurse arranges your transfer, she will notify you and provide instructions on when to arrive and how to prepare.
You need to have a full bladder for the procedure as a full bladder ensures good visualization of the lining of the uterus and proper placement of the embryos. It's important to drink the specific amount of liquid recommended 30 to 40 minutes ahead of time. You will review your cycle with the doctor and the number of embryos recommended for transfer.
Upon entering your procedure room, the embryologist will again confirm your last name and the number of embryos for transfer. The embryologist will load the transfer catheter in the embryology lab with the embryo s and then the doctor will insert the catheter into the uterus and push the embryo through with a small amount of fluid.
An external abdominal ultrasound provides visual guidance via a monitor to the doctor throughout the procedure. Once the doctor transfers the embryo, he or she will slowly remove the catheter. Since the embryo is invisible to the naked eye, the embryologist will then examine the catheter under a microscope in the lab to ensure that the catheter did indeed release the embryo. There are two protocols used for FET cycles. Both use hormones, including estrogen and progesterone, to prepare the uterus for embryo implantation.
Embryo transfer is usually done on either the 4th or 6th day of progesterone, depending on which day following fertilization the embryo had been frozen. There is no data that any one protocol works better than another and the protocol chosen is based upon your specific needs. It is not known how long embryos can be safely frozen, although there have been successful pregnancies even after being frozen for 10 years.
Most likely they can be stored indefinitely. A careful inventory is kept for all embryos in storage by our laboratory. The charge for embryo freezing includes the cost of storage for one year. Pregnancy testing is done days after transfer — depending on the stage of development of the embryos replaced and the preferences of the fertility clinic.
If pregnant, estrogen and progesterone are continued until about weeks of pregnancy and then weaned off. Pregnancy success rates with FET — frozen embryo transfers: Success rates for frozen embryo transfer cycles vary considerably by the program handling the case.
Ask your doctor for: The percentage of embryo thaw cycles that resulted in a transfer. Some thaws might result in degeneration of all of the embryos — therefore, no transfer is done. The live birth rate per transfer procedure for frozen-thawed embryos. Blastocyst implantation in an FET cycle Embryo implantation after frozen blastocyst transfers FET can be slightly delayed compared to that seen with fresh blastocyst transfer.
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